Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779001 | 0.88 | TRPV1 (0.49) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4780255 | 0.88 | TRPV1 (0.54) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4778225 | 0.84 | TRPV1 (0.50) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4778211 | 0.80 | KDM4E (0.51) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4778939 | 0.80 | TRPV1 (0.54) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4779265 | 0.80 | TRPV1 (0.50) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4777140 | 0.80 | TRPV1 (0.55) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4778078 | 0.78 | TRPV1 (0.48) | CCNE1CDK2CDK5SSTR4TRPV1 | |
| SCHEMBL4777154 | 0.77 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL4776317 | 0.76 | TRPV1 (0.60) | CCNE1CDK2CDK5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |