Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL1325211 | 0.98 | HDAC3 (0.42) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10389001 | 0.97 | HDAC3 (0.44) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Azelaic Acid SCHEMBL11666374 | 0.97 | HDAC3 (0.44) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Adipic Acid SCHEMBL29205731 | 0.97 | HDAC3 (0.41) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Sebacic Acid SCHEMBL1243174 | 0.97 | HDAC3 (0.44) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Sebacic Acid SCHEMBL11777506 | 0.95 | HDAC3 (0.43) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Succinic Acid SCHEMBL1326223 | 0.95 | ALDH1A1 (0.45) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Adipic Acid SCHEMBL28777798 | 0.92 | FFAR1 (0.46) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Adipic Acid SCHEMBL1325137 | 0.91 | HDAC3 (0.44) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Terephthalic Acid SCHEMBL28482093 | 0.91 | SMN1; SMN2 (0.42) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009067-A1 | ANTIFOULING COATING | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2008-01-24 | — | — | WO | disclosed |