Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 6/20 | 0.52 |
| ▸ | RB1 | P06400 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780786 | 0.88 | GRM5 (0.68) | GRM5L3MBTL1MEN1KMT2ARB1 | |
| SCHEMBL30804734 | 0.85 | GRM5 (0.67) | GRM5L3MBTL1MEN1KMT2ARB1 | |
| SCHEMBL1116603 | 0.77 | GRM5 (0.77) | GRM5L3MBTL1MEN1KMT2AHDAC1 | |
| SCHEMBL29639471 | 0.77 | GRM5 (0.68) | GRM5L3MBTL1MEN1KMT2A | |
| SCHEMBL4403625 | 0.74 | GRM5 (0.68) | GRM5L3MBTL1MEN1KMT2ARB1 | |
| SCHEMBL13294374 | 0.74 | GRM5 (0.81) | GRM5L3MBTL1MEN1KMT2A | |
| SCHEMBL3462086 | 0.74 | GRM5 (0.71) | GRM5L3MBTL1MEN1KMT2AHDAC1 | |
| SCHEMBL23573560 | 0.72 | GRM5 (0.69) | GRM5L3MBTL1MEN1KMT2AHDAC1 | |
| SCHEMBL23573558 | 0.72 | GRM5 (0.69) | GRM5L3MBTL1MEN1KMT2AHDAC1 | |
| SCHEMBL15962709 | 0.72 | GRM5 (0.69) | GRM5L3MBTL1MEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |