Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | RB1 | P06400 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780487 | 0.88 | GRM5 (0.60) | GRM5L3MBTL1KMT2AMEN1RB1 | |
| SCHEMBL1116603 | 0.84 | GRM5 (0.77) | GRM5L3MBTL1KMT2AMEN1HDAC1 | |
| SCHEMBL6820719 | 0.83 | GRM5 (0.68) | GRM5L3MBTL1KMT2AMEN1 | |
| SCHEMBL7799604 | 0.82 | MEN1 (0.54) | GRM5KMT2AMEN1HPGD | |
| SCHEMBL1543228 | 0.80 | HPGDS (0.62) | GRM5 | |
| SCHEMBL16496615 | 0.80 | HPGDS (0.62) | GRM5 | |
| SCHEMBL1543176 | 0.80 | HPGDS (0.62) | GRM5 | |
| SCHEMBL1543178 | 0.80 | HPGDS (0.62) | GRM5 | |
| SCHEMBL4403625 | 0.80 | GRM5 (0.68) | GRM5L3MBTL1KMT2AMEN1RB1 | |
| SCHEMBL13294374 | 0.80 | GRM5 (0.81) | GRM5L3MBTL1KMT2AMEN1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |