Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL8520431 | 0.93 | OPRM1 (0.45) | OPRM1HTR2AOPRK1OPRL1NPY5R | |
| SCHEMBL6071368 | 0.88 | OPRM1 (0.45) | OPRM1HTR2AOPRK1OPRL1NPY5R | |
| SCHEMBL27306600 | 0.86 | OPRM1 (0.43) | OPRM1HTR2ADPP4AKR1C1 | |
| SCHEMBL1958095 | 0.84 | OPRM1 (0.57) | OPRM1HTR2ANPY5RMEN1CYP2C9 | |
| Methyl Alcohol SCHEMBL8153725 | 0.83 | OPRM1 (0.41) | OPRM1HTR2AOPRK1OPRL1AKR1C1 | |
| SCHEMBL1637914 | 0.78 | HTR2A (0.44) | OPRM1HTR2AOPRK1OPRL1NPY5R | |
| SCHEMBL11880368 | 0.77 | HTR2A (0.50) | OPRM1HTR2AOPRK1OPRL1NPY5R | |
| SCHEMBL1670566 | 0.75 | OPRM1 (0.35) | OPRM1HTR2AOPRK1OPRL1NPY5R | |
| SCHEMBL28092237 | 0.73 | OPRM1 (0.36) | OPRM1HTR2ANPY5R | |
| SCHEMBL1959361 | 0.73 | HTR2A (0.47) | OPRM1HTR2ANPY5RCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039829-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |