Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206650 | 0.82 | GAA (0.52) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL4778443 | 0.78 | MGAM (0.44) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL7903603 | 0.78 | MGAM (0.47) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL4779353 | 0.76 | MGAM (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6110390 | 0.76 | MGAM (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4778475 | 0.74 | MGAM (0.47) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL7892532 | 0.74 | MGAM (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18334523 | 0.73 | GAA (0.41) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL10742501 | 0.73 | GAA (0.41) | MGAMGAASIMGAM2ALOX15 | |
| Cyclohexanol SCHEMBL4410504 | 0.72 | MGAM (0.40) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |