⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779051 | 0.79 | — | — | |
| SCHEMBL478035 | 0.79 | — | — | |
| SCHEMBL775066 | 0.79 | — | — | |
| SCHEMBL14890300 | 0.76 | — | — | |
| SCHEMBL775882 | 0.76 | — | — | |
| SCHEMBL82889 | 0.63 | — | — | |
| SCHEMBL13719072 | 0.63 | — | — | |
| SCHEMBL322524 | 0.63 | — | — | |
| SCHEMBL1173252 | 0.60 | — | — | |
| SCHEMBL1766118 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 734 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399209-A1 | NEW QUINOLINE DERIVATIVES | Elanco Animal Health GmbH (DE) | 2024-07-17 | — | — | EP | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| WO-2024118887-A1 | N-PHENYL-PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXAMIDE DERIVATIVES AS WILD TYPE C-KIT KINASE INHIBITORS FOR THE TREATMENT OF URTICARIA | BLUEPRINT MEDICINES CORPORATION (US) | 2024-06-06 | — | — | WO | claimed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | claimed |
| WO-2024104932-A1 | ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-23 | — | — | WO | claimed |
| CN-118019736-A | Molecular gel compound designed based on cereblon protein and application thereof | 标新生物医药科技(上海)有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-4363058-A1 | AZETIDINYL PYRIMIDINES AND USES THEREOF | Aerie Pharmaceuticals, Inc. (US) | 2024-05-08 | — | — | EP | claimed |
| US-20240140919-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. | 2024-05-02 | — | — | US | claimed |
| CN-117957223-A | Quinoline derivatives | 礼蓝动物保健有限公司 | 2024-04-30 | — | — | CN | claimed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | claimed |
| EP-0640142-A1 | PROCESS FOR PRODUCTION OF AVERMECTINS AND CULTURES THEREFOR | PFIZER INC. (US) | 1995-03-01 | — | — | EP | claimed |
| EP-0276103-B1 | Process for production of B avermectins and cultures therefor | PFIZER (US) | 1993-10-20 | — | — | EP | claimed |
| WO-1993019194-A1 | PROCESS FOR PRODUCTION OF AVERMECTINS AND CULTURES THEREFOR | PFIZER INC. (US) | 1993-09-30 | — | — | WO | claimed |
| EP-0284176-B1 | PROCESS FOR PRODUCTION OF AVERMECTINS AND CULTURES THEREFOR | PFIZER INC. (US) | 1993-08-25 | — | — | EP | claimed |
| EP-0313297-B1 | PROCESS FOR PRODUCTION OF AVERMECTIN AGLYCONES AND CULTURES THEREFOR | PFIZER INC. (US) | 1993-05-19 | — | — | EP | claimed |
| EP-0276131-B1 | NON-NATURAL DEMETHYLAVERMECTINS AND PROCESS THEREFOR | PFIZER INC. (US) | 1993-04-07 | — | — | EP | claimed |
| EP-0313297-A2 | Process for production of avermectin aglycones and cultures therefor | PFIZER INC. (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0284176-A2 | Process for production of avermectins and cultures therefor | PFIZER INC. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0276103-A2 | Process for production of B avermectins and cultures therefor | PFIZER INC. (US) | 1988-07-27 | — | — | EP | claimed |
| EP-0276131-A2 | Non-natural demethylavermectins and process therefor | PFIZER INC. (US) | 1988-07-27 | — | — | EP | claimed |