Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777957 | 0.84 | ADRA1A (0.39) | ADRA1A | |
| SCHEMBL14291153 | 0.80 | ACKR3 (0.39) | POLBHTR1A | |
| SCHEMBL14291147 | 0.80 | KDM5A (0.42) | HTR2CHTR2BHTR1A | |
| SCHEMBL14291055 | 0.78 | HTR2C (0.34) | P2RY12HTR2CHTR2BOPRM1 | |
| SCHEMBL4796232 | 0.78 | HTR2C (0.34) | P2RY12HTR2CHTR2BOPRM1 | |
| SCHEMBL4796228 | 0.78 | HTR2C (0.34) | P2RY12HTR2CHTR2BOPRM1 | |
| SCHEMBL14291585 | 0.77 | MEN1 (0.44) | — | |
| SCHEMBL14291581 | 0.77 | MEN1 (0.44) | — | |
| SCHEMBL4849117 | 0.77 | ADRA1A (0.37) | ADRA1A | |
| SCHEMBL14290685 | 0.77 | KDM5A (0.39) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |