Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.76 |
| ▸ | NPC1 | O15118 | 14/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.76 |
| ▸ | HPGD | P15428 | 5/20 | 0.76 |
| ▸ | PKM | P14618 | 5/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.70 |
| ▸ | RELA | Q04206 | 2/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6389879 | 0.88 | RAB9A (0.97) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4728826 | 0.84 | RAB9A (0.76) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL20370639 | 0.83 | RAB9A (1.00) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8342931 | 0.83 | RAB9A (0.78) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL12848509 | 0.82 | RAB9A (0.76) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL12848506 | 0.81 | RAB9A (0.79) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL6525392 | 0.81 | RAB9A (0.79) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL12848498 | 0.80 | RAB9A (0.68) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6387639 | 0.80 | RAB9A (0.64) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL14764811 | 0.79 | TLR9 (0.63) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |