Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908267 | 0.75 | APOBEC3G (0.53) | MAPK1APOBEC3GALDH1A1TDP1RORC | |
| SCHEMBL756576 | 0.72 | TDP1 (0.39) | MAPK1APOBEC3GALDH1A1TDP1RORC | |
| SCHEMBL12084059 | 0.71 | APOBEC3G (0.52) | APOBEC3GALDH1A1TDP1HTR6NR1H3 | |
| SCHEMBL14612610 | 0.70 | TDP1 (0.46) | MAPK1APOBEC3GTDP1RORCNR1I2 | |
| SCHEMBL13328880 | 0.70 | APOBEC3G (0.50) | APOBEC3GALDH1A1NR1I2HTR6NR1H2 | |
| SCHEMBL3279350 | 0.68 | APOBEC3G (0.48) | APOBEC3GALDH1A1TDP1NR1I2NR1H2 | |
| SCHEMBL9812438 | 0.68 | APOBEC3G (0.48) | APOBEC3GALDH1A1TDP1HTR6NR1H3 | |
| SCHEMBL26387747 | 0.68 | APOBEC3G (0.48) | APOBEC3GALDH1A1TDP1NR1I2HTR6 | |
| SCHEMBL6900015 | 0.68 | APOBEC3G (0.59) | APOBEC3GALDH1A1TDP1NR1I2HTR6 | |
| SCHEMBL6497006 | 0.68 | MAPK1 (0.65) | MAPK1ALDH1A1TDP1RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008431-A2 | HETEROARYL SULFONAMIDES AND CCR2/CCR9 | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |