Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754506 | 0.86 | MAPK1 (0.36) | TDP1MAPK1ALDH1A1LMNAHTT | |
| SCHEMBL756945 | 0.76 | LMNA (0.38) | MAPK1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL21169198 | 0.74 | LMNA (0.49) | TDP1MAPK1ALDH1A1ESR1L3MBTL1 | |
| SCHEMBL4780960 | 0.72 | MAPK1 (0.43) | TDP1MAPK1ALDH1A1RORCAPOBEC3G | |
| SCHEMBL10312363 | 0.69 | MAPK1 (0.50) | TDP1MAPK1ESR1APOBEC3GLMNA | |
| SCHEMBL10312362 | 0.68 | TDP1 (0.47) | TDP1MAPK1ALDH1A1ESR1APOBEC3G | |
| SCHEMBL4024323 | 0.68 | SIGMAR1 (0.39) | MAPK1ALDH1A1RORCNR1I2LMNA | |
| SCHEMBL23536176 | 0.66 | LMNA (0.50) | TDP1MAPK1ALDH1A1RORCL3MBTL1 | |
| SCHEMBL10312373 | 0.66 | ESR1 (0.57) | MAPK1ESR1RORCL3MBTL1NR1I2 | |
| SCHEMBL21565813 | 0.66 | ALDH1A1 (0.53) | TDP1MAPK1ALDH1A1APOBEC3GL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138272-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | ELAN PHARMACEUTICALS, INC. | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | PIGO, MANBA, OAT | TDP1 869/4885MAPK1 3922/4885ALDH1A1 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.