Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780793 | 0.88 | PTGER4 (0.55) | PTGER4HDAC6MAPTTP53HDAC1 | |
| SCHEMBL5326258 | 0.83 | PTGER4 (0.50) | PTGER4MAPTTP53CXCR3DNM1 | |
| SCHEMBL11829790 | 0.82 | PTGER4 (0.72) | PTGER4HDAC6MAPTHDAC3HDAC4 | |
| SCHEMBL8800910 | 0.81 | PTGER4 (0.56) | PTGER4HDAC6MAPTHDAC3HDAC4 | |
| SCHEMBL5119647 | 0.80 | PTGER4 (0.70) | PTGER4HDAC6HDAC1POLBKDM4E | |
| SCHEMBL5660529 | 0.80 | PTGER4 (0.70) | PTGER4HDAC6HDAC1POLBKDM4E | |
| SCHEMBL5322058 | 0.80 | HDAC6 (0.51) | HDAC6MAPTTP53CXCR3DNM1 | |
| SCHEMBL4687926 | 0.79 | PTGER4 (0.72) | PTGER4MAPTPOLBKDM4EPKM | |
| SCHEMBL29749450 | 0.79 | PTGER4 (0.72) | PTGER4MAPTPOLBKDM4EPKM | |
| SCHEMBL7143861 | 0.79 | PTGER4 (0.68) | PTGER4MAPTPOLBKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |