Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899271 | 0.81 | PTGER4 (0.58) | PTGER4 | |
| SCHEMBL4781011 | 0.81 | PTGER4 (0.61) | PTGER4BCHEACHEHDAC6HDAC3 | |
| SCHEMBL13634962 | 0.81 | PTGER4 (0.61) | PTGER4MAPTMEN1KMT2ALMNA | |
| SCHEMBL29643279 | 0.80 | BCHE (0.67) | BCHEACHEHDAC6CYP19A1FABP4 | |
| SCHEMBL11209828 | 0.80 | BCHE (0.67) | BCHEACHEHDAC6CYP19A1FABP4 | |
| SCHEMBL31222144 | 0.80 | PTGER4 (0.61) | PTGER4MAPTMEN1KMT2ALMNA | |
| SCHEMBL7172636 | 0.80 | PTGER4 (0.61) | PTGER4MAPTMEN1KMT2ALMNA | |
| SCHEMBL5519249 | 0.79 | PSEN1 (0.57) | PTGER4 | |
| SCHEMBL29002800 | 0.78 | PTGER4 (0.50) | PTGER4MAPTMEN1KMT2ALMNA | |
| SCHEMBL689666 | 0.78 | CYP19A1 (0.64) | PTGER4HDAC6CYP19A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |