Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.39 |
| ▸ | MTOR | P42345 | 3/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782401 | 1.00 | PIK3CA (0.39) | PIK3CAMTORIDH2IRAK1IRAK4 | |
| SCHEMBL4784076 | 0.90 | PIK3CA (0.41) | PIK3CAMTORIRAK1IRAK4 | |
| SCHEMBL4785092 | 0.90 | PIK3CA (0.41) | PIK3CAMTORIRAK1IRAK4 | |
| SCHEMBL4784491 | 0.90 | PIK3CA (0.41) | PIK3CAMTORIRAK1IRAK4 | |
| SCHEMBL4784166 | 0.89 | PIK3CA (0.43) | PIK3CAMTOR | |
| SCHEMBL4884098 | 0.89 | PIK3CA (0.45) | PIK3CAMTOR | |
| SCHEMBL4784954 | 0.88 | PIK3CA (0.44) | PIK3CAMTORP2RY12 | |
| SCHEMBL4785820 | 0.86 | PIK3CA (0.40) | PIK3CAMTORIDH2 | |
| SCHEMBL4785561 | 0.86 | PIK3CA (0.43) | PIK3CAMTOR | |
| SCHEMBL4785311 | 0.86 | PIK3CA (0.41) | PIK3CAMTORIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |