SCHEMBL4781371

SCHEMBL4781371

CCC(CC)C(=O)OC1CCCCC1OC(=O)C(CC)CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
ADRA1A P35348 1/20 0.37
CHRNA4 P43681 1/20 0.37
HTR3A P46098 1/20 0.37
KCNH2 Q12809 1/20 0.37
EPHX1 P07099 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
SERPINE1 P05121 2/20 0.34
NAAA Q02083 2/20 0.34
CYP2D6 P10635 1/20 0.34
CHRM4 P08173 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3181537 0.86 CA2 (0.56) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL3181529 0.86 CA2 (0.56) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL16065512 0.84 KDM4E (0.33) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL11164322 0.84 CHRM1 (0.53) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL14875486 0.83 EPHX1 (0.48) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL3186547 0.82 CA2 (0.56) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL3186549 0.82 CA2 (0.56) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL28093842 0.82 CA2 (0.40) CHRM2CHRM1CHRM3ADRA1ACHRNA4
SCHEMBL3266694 0.82 EPHX2 (0.37) EPHX1KDM4EALDH1A1MEN1KMT2A
SCHEMBL5827222 0.82 EPHX1 (0.52) CHRM2CHRM1CHRM3ADRA1ACHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008004788-A1 NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF WONKISOPHARM CO., LTD. (KR) 2008-01-10 WO claimed
US-8420853-B2 Derivatives of cyclic compound and the use thereof Wonkisopharm Co., Ltd (KR) 2013-04-16 US disclosed