Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.51 |
| ▸ | CNR2 | P34972 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540077 | 1.00 | CNR1 (0.51) | CNR1CNR2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2539512 | 0.95 | CNR1 (0.47) | CNR1CNR2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2537616 | 0.95 | CNR1 (0.47) | CNR1CNR2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2538690 | 0.95 | CNR1 (0.52) | CNR1CNR2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2538885 | 0.93 | RAB9A (0.47) | CNR1CNR2L3MBTL1KDREGFR | |
| SCHEMBL2537283 | 0.92 | CNR1 (0.55) | CNR1CNR2KMT2AALDH1A1MEN1 | |
| SCHEMBL2536146 | 0.92 | CNR1 (0.54) | CNR1CNR2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2545412 | 0.91 | CNR1 (0.49) | CNR1CNR2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2535596 | 0.91 | CNR1 (0.46) | CNR1CNR2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2545237 | 0.91 | CNR1 (0.43) | CNR1CNR2L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |
| WO-2008062424-A2 | SUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |