⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781669 | 1.00 | — | — | |
| SCHEMBL4781662 | 1.00 | — | — | |
| SCHEMBL3434947 | 0.71 | — | — | |
| SCHEMBL499165 | 0.71 | — | — | |
| SCHEMBL499166 | 0.71 | — | — | |
| SCHEMBL9404080 | 0.69 | — | — | |
| SCHEMBL9404081 | 0.69 | — | — | |
| SCHEMBL385908 | 0.67 | — | — | |
| SCHEMBL385909 | 0.67 | — | — | |
| SCHEMBL423889 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850268-B2 | Metathesis catalysts and methods thereof | TRUSTEES OF BOSTON COLLEGE (US) | 2017-12-26 | — | — | US | disclosed |
| EP-1200390-B1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | SPEEDEL PHARMA AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008006394-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE (4E)-5- HALO-2-ALKYLPENT-4-ENOIC ACIDS AND THEIR ESTER DERIVATIVES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2008-01-17 | — | — | WO | disclosed |
| US-7132569-B2 | Preparation of N-substituted 2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amides | SPEEDEL PHARMA AG (CH) | 2006-11-07 | — | — | US | disclosed |
| US-7009078-B1 | Production of N-substituted 2,7-dialkyl-4-hydroxy-5-amino-8-arly-octanoylamides | SPEEDEL PHARMA AG (CH) | 2006-03-07 | — | — | US | disclosed |
| US-20060041169-A1 | PREPARATION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES | NODEN PHARMA DAC (IE) | 2006-02-23 | — | — | US | disclosed |
| US-6800769-B2 | CHEMICAL INTERMEDIATES | SPEEDEL PHARMA AG (CH) | 2004-10-05 | — | — | US | disclosed |
| US-6777574-B1 | RENIN-INHIBITING PROPERTIES; ANTIHYPERTENSIVE AGENTS | SPEEDEL PHARMA AG (CH) | 2004-08-17 | — | — | US | disclosed |
| EP-1303478-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES | SPEEDEL PHARMA AG (CH) | 2004-05-26 | — | — | EP | disclosed |
| EP-1200384-B1 | 2-ALKYL-5-HALOGEN-PENT-4-ENE CARBOXYLIC ACIDS AND THEIR PRODUCTION | SPEEDEL PHARMA AG (CH) | 2004-04-28 | — | — | EP | disclosed |
| US-20030181765-A1 | Process for the preparation of substituted octanoyl amides | NODEN PHARMA DAC (IE) | 2003-09-25 | — | — | US | disclosed |
| EP-1303478-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES | Speedel Pharma AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1200390-A1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | Speedel Pharma AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| WO-2002008172-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES | SPEEDEL PHARMA AG (CH) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001009083-A1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | SPEEDEL PHARMA AG (CH) | 2001-02-08 | — | — | WO | disclosed |
| EP-0271240-A2 | Fluorobenzyl esters | ZENECA LIMITED (GB) | 1988-06-15 | — | — | EP | disclosed |