⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781664 | 1.00 | — | — | |
| SCHEMBL4781662 | 1.00 | — | — | |
| SCHEMBL3434947 | 0.71 | — | — | |
| SCHEMBL499165 | 0.71 | — | — | |
| SCHEMBL499166 | 0.71 | — | — | |
| SCHEMBL9404080 | 0.69 | — | — | |
| SCHEMBL9404081 | 0.69 | — | — | |
| SCHEMBL385908 | 0.67 | — | — | |
| SCHEMBL385909 | 0.67 | — | — | |
| SCHEMBL423889 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104058990-B | A kind of aliskiren or the method for separating and analyzing of its salt | 博瑞生物医药（苏州）股份有限公司 | 2017-03-15 | — | — | CN | disclosed |
| CN-104058990-A | Separation analysis method of aliskiren and salts thereof | BRIGHTGENE BIO MEDICAL TECHNOLOGY CO LTD | 2014-09-24 | — | — | CN | disclosed |
| WO-2008006394-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE (4E)-5- HALO-2-ALKYLPENT-4-ENOIC ACIDS AND THEIR ESTER DERIVATIVES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2008-01-17 | — | — | WO | disclosed |
| US-7132569-B2 | Preparation of N-substituted 2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amides | SPEEDEL PHARMA AG (CH) | 2006-11-07 | — | — | US | disclosed |
| US-7009078-B1 | Production of N-substituted 2,7-dialkyl-4-hydroxy-5-amino-8-arly-octanoylamides | SPEEDEL PHARMA AG (CH) | 2006-03-07 | — | — | US | disclosed |
| US-20060041169-A1 | PREPARATION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES | NODEN PHARMA DAC (IE) | 2006-02-23 | — | — | US | disclosed |
| US-6800769-B2 | CHEMICAL INTERMEDIATES | SPEEDEL PHARMA AG (CH) | 2004-10-05 | — | — | US | disclosed |
| US-6777574-B1 | RENIN-INHIBITING PROPERTIES; ANTIHYPERTENSIVE AGENTS | SPEEDEL PHARMA AG (CH) | 2004-08-17 | — | — | US | disclosed |
| EP-1303478-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES | SPEEDEL PHARMA AG (CH) | 2004-05-26 | — | — | EP | disclosed |
| EP-1200390-A1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | Speedel Pharma AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| EP-1200384-A1 | 2-ALKYL-5-HALOGEN-PENT-4-ENE CARBOXYLIC ACIDS AND THEIR PRODUCTION | Speedel Pharma AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009079-A1 | 2-ALKYL-5-HALOGEN-PENT-4-ENE CARBOXYLIC ACIDS AND THEIR PRODUCTION | SPEEDEL PHARMA AG (CH) | 2001-02-08 | — | — | WO | disclosed |
| WO-2001009083-A1 | PRODUCTION OF N-SUBSTITUTED 2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYLAMIDES | SPEEDEL PHARMA AG (CH) | 2001-02-08 | — | — | WO | disclosed |
| US-5010200-A | Insecticide intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-23 | — | — | US | disclosed |
| US-4962109-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-09 | — | — | US | disclosed |
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4762835-A | INSECTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-09 | — | — | US | disclosed |
| EP-0271240-A2 | Fluorobenzyl esters | ZENECA LIMITED (GB) | 1988-06-15 | — | — | EP | disclosed |
| EP-0227415-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |