⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106130 | 0.93 | — | — | |
| SCHEMBL6823225 | 0.74 | — | — | |
| SCHEMBL6822598 | 0.74 | — | — | |
| SCHEMBL12924122 | 0.71 | — | — | |
| SCHEMBL8507132 | 0.70 | — | — | |
| SCHEMBL3866736 | 0.70 | HTT (0.31) | — | |
| SCHEMBL4306204 | 0.70 | — | — | |
| SCHEMBL3414996 | 0.70 | — | — | |
| SCHEMBL28050721 | 0.70 | NR1I2 (0.30) | — | |
| SCHEMBL2524434 | 0.68 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822172-B2 | PROCESS FOR PREPARING FLUOROMETHYL 1,1,1,3,3,3-HEXAFLUOROISOPROPYL ETHER | CENTRAL GLASS CO LTD (JP) | 2004-10-06 | — | — | EP | claimed |
| EP-0822172-B1 | PROCESS FOR PREPARING FLUOROMETHYL 1,1,1,3,3,3-HEXAFLUOROISOPROPYL ETHER | CENTRAL GLASS CO LTD (JP) | 2001-11-28 | — | — | EP | claimed |
| US-5811596-A | BRINGING A POLYETHER INTO CONTACT WITH A MEDIUM COMPRISING HYDROGEN FLUORIDE AND AND ACCELERANT | CENTRAL GLASS CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| EP-0822172-A1 | PROCESS FOR PREPARING FLUOROMETHYL 1,1,1,3,3,3-HEXAFLUOROISOPROPYL ETHER | CENTRAL GLASS COMPANY, LIMITED (JP) | 1998-02-04 | — | — | EP | claimed |
| WO-2008048947-A2 | APPARATUS FOR AND RELATED METHOD OF INHIBITING LEWIS ACID DEGRADATION IN A VAPORIZER | ABBOTT LABORATORIES (US) | 2008-04-24 | — | — | WO | disclosed |
| US-20080087283-A1 | APPARATUS FOR AND RELATED METHOD OF INHIBITING LEWIS ACID DEGRADATION IN A VAPORIZER | ABBOTT LABORATORIES (US) | 2008-04-17 | — | — | US | disclosed |
| US-20060148906-A1 | Fluoroether compositions and methods for inhibiting their degradation in the presence of a lewis acid | BIENIARZ CHRISTOPHER | 2006-07-06 | — | — | US | disclosed |
| EP-1114641-B1 | Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid | ABBOTT LAB (US) | 2006-03-22 | — | — | EP | disclosed |
| CN-1560003-A | Fluoroether compositions and methods for inhibiting degradation thereof in the presence of lewis acids | ���Ͽع�����˾ | 2005-01-05 | — | — | CN | disclosed |
| US-20040048932-A1 | Fluoroether compositions and methods for inhibiting their degradation in the presnce of a lewis acid | BIENIARZ CHRISTOPHER (US) | 2004-03-11 | — | — | US | disclosed |
| US-6677492-B2 | SEVOFLURANE | ABBOTT LABORATORIES | 2004-01-13 | — | — | US | disclosed |
| US-20030130359-A1 | Fluoroether compositions and methods for inhibiting their degradation in the presence of a lewis acid | ABBVIE INC. | 2003-07-10 | — | — | US | disclosed |
| US-20020016373-A1 | Fluoroether compositions and methods for inhibiting their degradation in the presence of a lewis acid | ABBVIE INC. | 2002-02-07 | — | — | US | disclosed |
| US-6288127-B1 | ADDING LEWIS ACID INHIBITOR | ABBOTT LABORATORIES & CENTRAL GLASS CO LTD | 2001-09-11 | — | — | US | disclosed |
| EP-1114641-A2 | Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid | Abbott Laboratories (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0967975-B1 | FLUOROETHER COMPOSITIONS AND METHODS FOR INHIBITING THEIR DEGRADATION IN THE PRESENCE OF A LEWIS ACID | ABBOTT LAB (US) | 2001-06-13 | — | — | EP | disclosed |
| CN-1244797-A | Fluoroether compositions and methods for inhibiting degradation thereof in the presence of lewis acids | ABBOTT LAB (US) | 2000-02-16 | — | — | CN | disclosed |
| EP-0967975-A1 | FLUOROETHER COMPOSITIONS AND METHODS FOR INHIBITING THEIR DEGRADATION IN THE PRESENCE OF A LEWIS ACID | Abbott Laboratories (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5990176-A | ANESTHETIC COMPOSITION OF SEVOFLURANE AND A STABILIZING AMOUNT OF A LEWIS ACID INHIBITOR SELECTED FROM THE GROUP CONSISTING OF WATER, BUTYLATED HYDROXYTOLUENE, METHYLPARABEN, PROPYLPARABEN, PROPOFOL, AND THYMOL | ABBOTT LABORATORIES (US) | 1999-11-23 | — | — | US | disclosed |
| WO-1998032430-A1 | FLUOROETHER COMPOSITIONS AND METHODS FOR INHIBITING THEIR DEGRADATION IN THE PRESENCE OF A LEWIS ACID | ABBOTT LABORATORIES (US) | 1998-07-30 | — | — | WO | disclosed |