⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772664 | 0.83 | — | — | |
| SCHEMBL1936262 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL452616 | 0.81 | TSHR (0.32) | — | |
| SCHEMBL47820 | 0.80 | TSHR (0.41) | — | |
| SCHEMBL28391050 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL19359798 | 0.77 | — | — | |
| SCHEMBL9704864 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL222174 | 0.77 | — | — | |
| SCHEMBL609520 | 0.77 | — | — | |
| SCHEMBL9761916 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022262-A1 | SALT OF ENDOTHELIN A (ETA) RECEPTOR ANTAGONIST COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2024-02-01 | — | — | WO | disclosed |
| WO-2023208108-A1 | COMPOUND FOR REDUCING URIC ACID | 江苏新元素医药科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023208103-A1 | COMPOUND CAPABLE OF BEING USED FOR GOUT | 江苏新元素医药科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| EP-3486242-B1 | OXOPICOLINAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2021-12-08 | — | — | EP | disclosed |
| CN-113683614-A | Fused tricyclic pyridazinone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-109863151-B | Fused tricyclic pyridazinone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2021-09-10 | — | — | CN | disclosed |
| US-11084808-B2 | Oxopicolinamide derivative, preparation method therefor and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2021-08-10 | — | — | US | disclosed |
| CN-112969687-A | Quinoline derivatives as alpha 4 beta 7 integrin inhibitors | 吉利德科学公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-112154145-A | Piperazine azaspiro derivatives | 辉瑞大药厂 | 2020-12-29 | — | — | CN | disclosed |
| US-20200199115-A1 | OXOPICOLINAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2020-06-25 | — | — | US | disclosed |
| CN-1007811-B | PROCESS FOR PREPARING CARBAMIC ACID DERIVATIVES | POUDRES & EXPLOSIFS STE NALE (FR) | 1990-05-02 | — | — | CN | disclosed |
| US-4918068-A | ACTIVE AGAINST GRAM POSITIVE BACTERIA | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0362967-A1 | Nucleoside derivatives | NYCOMED IMAGING AS (NO) | 1990-04-11 | — | — | EP | disclosed |
| CN-1033809-A | 6-chloro-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno-(2,3-e)-1,2-thiazines-3-Carboxylamide 1,1-dioxide enol ether compounds, its preparation method and application | CL PHARMA (AT) | 1989-07-12 | — | — | CN | disclosed |
| US-4826833-A | ANTIBIOTICS | PFIZER INC. (US) | 1989-05-02 | — | — | US | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| EP-0236231-A2 | Novel cephem compounds | MEIJI SEIKA KAISHA LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
| CN-85102030-A | The preparation method of the ethers parent medicine of antiphlogiston Xi Kamu | — | 1987-01-31 | — | — | CN | disclosed |
| EP-0113101-A1 | 6-(1-Hydroxyethyl)-2-SR8-1-methyl-1-carbadethiapen-2-em-3-carboxylic acid esters | MERCK & CO. INC. (US) | 1984-07-11 | — | — | EP | disclosed |