⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728550 | 0.83 | LMNA (0.48) | — | |
| SCHEMBL14627140 | 0.80 | — | — | |
| SCHEMBL745345 | 0.80 | — | — | |
| SCHEMBL10673600 | 0.80 | LMNA (0.39) | — | |
| Pentabamate SCHEMBL636717 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL47820 | 0.78 | TSHR (0.41) | — | |
| SCHEMBL1269148 | 0.78 | — | — | |
| SCHEMBL8755732 | 0.76 | — | — | |
| SCHEMBL18043494 | 0.76 | — | — | |
| SCHEMBL28623541 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873020-A | RAS inhibitors | 锐新医药公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114901366-A | RAS inhibitors | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |
| US-5055567-A | For dyeing polyester | CIBA-GEIGY CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0144840-A2 | Optically active beta-lactams and method of their production | Takeda Chemical Industries, Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |