Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 19/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739058 | 0.87 | FASN (0.49) | FASN | |
| SCHEMBL4738130 | 0.86 | FASN (0.48) | FASN | |
| SCHEMBL4734651 | 0.82 | FASN (0.52) | FASN | |
| SCHEMBL4201413 | 0.80 | FASN (0.59) | FASN | |
| SCHEMBL4739352 | 0.76 | FASN (0.55) | FASN | |
| SCHEMBL4782520 | 0.76 | FASN (0.51) | FASN | |
| SCHEMBL4739036 | 0.74 | FASN (0.57) | FASN | |
| SCHEMBL4175661 | 0.73 | FASN (0.60) | FASN | |
| SCHEMBL4193597 | 0.72 | FASN (0.62) | FASN | |
| SCHEMBL4170775 | 0.70 | FASN (0.76) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075064-A1 | PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |