SCHEMBL4782380

SCHEMBL4782380

O=C1N=NC(=O)C(c2ccccc2)(c2ccccc2)N1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.47
BLM P54132 2/20 0.47
PMP22 Q01453 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CACNA1F O60840 1/20 0.47
MAPT P10636 1/20 0.47
HTR2A P28223 1/20 0.47
HRH1 P35367 1/20 0.47
SCN1A P35498 1/20 0.47
SCN4A P35499 1/20 0.47
CACNA1D Q01668 1/20 0.47
KCNH2 Q12809 1/20 0.47
CACNA1S Q13698 1/20 0.47
CACNA1C Q13936 1/20 0.47
SCN5A Q14524 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
AKR1B1 P15121 1/20 0.40
LMNA P02545 2/20 0.39
GLA P06280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11836878 0.83 CYP2C9 (0.50) CYP2C9BLMPMP22ALDH1A1CACNA1F
Phenytoin SCHEMBL29415216 0.73 CYP2C9 (0.49) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL7327872 0.71 BACE1 (0.46) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL325055 0.71 CYP2C9 (0.46) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL10849988 0.67 ALDH1A1 (0.42) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL17471508 0.67 ALDH1A1 (0.42) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL8665106 0.67 ALDH1A1 (0.42) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL11929302 0.67 ALDH1A1 (0.42) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL7890272 0.66 CYP2C9 (0.39) CYP2C9BLMPMP22ALDH1A1CACNA1F
SCHEMBL6595996 0.65 CYP2C9 (0.44) CYP2C9BLMPMP22ALDH1A1CACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008027772-A2 ULTRAFAST IMMUNOEXTRACTION/DISPLACEMENT ASSAYS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2008-03-06 WO disclosed