Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4782526 | 0.96 | LMNA (0.32) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| SCHEMBL4777960 | 0.96 | TSHR (0.35) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| Formic Acid SCHEMBL4794874 | 0.92 | CHRM3 (0.34) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| Formic Acid SCHEMBL4794869 | 0.88 | CHRM3 (0.34) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| SCHEMBL4782484 | 0.88 | CHRM3 (0.36) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| SCHEMBL4726613 | 0.82 | TSHR (0.35) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| SCHEMBL4727024 | 0.81 | CHRM2 (0.33) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| SCHEMBL4779685 | 0.81 | CHRM2 (0.33) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| SCHEMBL4725244 | 0.81 | KCNH2 (0.36) | LMNACHRM2CHRM1SLC6A3KCNH2 | |
| SCHEMBL523789 | 0.81 | CHRM2 (0.33) | LMNACHRM2CHRM1SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |