Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL17333657 | 0.79 | MEN1 (0.76) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL29184151 | 0.77 | ALDH1A1 (0.63) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL11379 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL340272 | 0.75 | ALDH1A1 (0.70) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL572741 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL31211562 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TSHRGLAMEN1KMT2A | |
| Water SCHEMBL27864846 | 0.73 | ALDH1A1 (0.68) | ALDH1A1TSHRGLAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27451829 | 0.73 | ALDH1A1 (0.68) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL28905923 | 0.73 | ALDH1A1 (0.53) | ALDH1A1TSHRGLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016676-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | disclosed |