Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 11/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 11/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727513 | 0.88 | CHRM3 (0.44) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4793046 | 0.84 | CHRM3 (0.43) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4782462 | 0.79 | KDM4C (0.41) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4725344 | 0.79 | NOTUM (0.36) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2238914 | 0.74 | CYP2D6 (0.66) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL28257085 | 0.74 | CYP2D6 (0.66) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4726296 | 0.74 | KCNH2 (0.39) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1848858 | 0.71 | CHRM3 (0.40) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1848860 | 0.71 | CHRM3 (0.40) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1846153 | 0.70 | CYP2D6 (0.39) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |