Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973412 | 0.83 | GBA1 (0.45) | CPN1CPB2SLC6A3KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL10568595 | 0.82 | GBA1 (0.44) | CPN1CPB2SLC6A3KDM1AMAOB | |
| SCHEMBL7895852 | 0.77 | SLC6A3 (0.33) | CPN1CPB2CHEK1SLC6A3PRKCZ | |
| Trifluoroacetic Acid SCHEMBL20472460 | 0.75 | CPN1 (0.39) | CPN1CPB2SLC6A3HTR2AHTR2C | |
| SCHEMBL4563760 | 0.75 | HIF1A (0.55) | SLC6A3 | |
| SCHEMBL27310465 | 0.73 | SLC6A2 (0.42) | SLC6A3 | |
| SCHEMBL3616023 | 0.73 | SLC6A4 (0.48) | SLC6A3 | |
| SCHEMBL1862768 | 0.73 | SLC6A4 (0.48) | SLC6A3 | |
| SCHEMBL3616019 | 0.73 | SLC6A4 (0.48) | SLC6A3 | |
| SCHEMBL1862764 | 0.73 | SLC6A4 (0.48) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937271-A1 | MICROANGIOPATHY TREATMENT AND PREVENTION | Bayer HealthCare AG (DE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007042146-A1 | MICROANGIOPATHY TREATMENT AND PREVENTION | BAYER HEALTHCARE AG (DE) | 2007-04-19 | — | — | WO | disclosed |