Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.48 |
| ▸ | MTOR | P42345 | 8/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786261 | 0.93 | PIK3CA (0.46) | PIK3CAMTORPIK3CGPIK3R1 | |
| SCHEMBL4782724 | 0.92 | PIK3CA (0.57) | PIK3CAMTORPIK3CGPIK3R1 | |
| SCHEMBL4785905 | 0.89 | ESR1 (0.44) | PIK3CAMTORPIK3CG | |
| SCHEMBL4884094 | 0.89 | PIK3CA (0.44) | PIK3CAMTORPIK3CGPIK3R1 | |
| SCHEMBL4783216 | 0.88 | ESR1 (0.45) | PIK3CAMTORPIK3CG | |
| SCHEMBL4785891 | 0.87 | PIK3CA (0.46) | PIK3CAMTORPIK3CGPIK3R1 | |
| SCHEMBL4784160 | 0.87 | PIK3CA (0.42) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4784132 | 0.86 | PIK3CA (0.44) | PIK3CAMTORPIK3R1 | |
| SCHEMBL4785307 | 0.84 | PIK3CA (0.40) | PIK3CAMTORPIK3CGPIK3R1 | |
| SCHEMBL4785552 | 0.84 | PIK3CA (0.42) | PIK3CAMTORPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |