Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 3/20 | 0.37 |
| ▸ | ESRRA | P11474 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785905 | 0.99 | ESR1 (0.44) | ESR1ESR2PIK3CAKDM2BESRRG | |
| SCHEMBL4786261 | 0.91 | PIK3CA (0.46) | ESR1ESR2PIK3CAMTORPIK3CG | |
| SCHEMBL4783015 | 0.88 | PIK3CA (0.48) | PIK3CAMTORPIK3CG | |
| SCHEMBL4782297 | 0.87 | PIK3CA (0.43) | ESR1ESR2PIK3CAMTOR | |
| SCHEMBL4783923 | 0.87 | HRH4 (0.43) | ESR1ESR2PIK3CAMTOR | |
| SCHEMBL4884094 | 0.86 | PIK3CA (0.44) | ESR1ESR2PIK3CAMTORPIK3CB | |
| SCHEMBL4784160 | 0.86 | PIK3CA (0.42) | ESR1ESR2PIK3CAMTOR | |
| SCHEMBL4784640 | 0.86 | ADORA3 (0.43) | ESR1ESR2PIK3CAMTORPIK3CG | |
| SCHEMBL4784132 | 0.85 | PIK3CA (0.44) | ESR1ESR2PIK3CAMTOR | |
| SCHEMBL4784088 | 0.85 | PIK3CA (0.43) | ESR1ESR2PIK3CAMTORHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |