Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PRNP | P04156 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11799344 | 0.98 | NCF1 (0.59) | NCF1MGAMMEN1KMT2ACNR2 | |
| SCHEMBL11799340 | 0.84 | NCF1 (0.59) | NCF1MGAMMEN1KMT2ACNR2 | |
| SCHEMBL6276706 | 0.84 | NCF1 (0.59) | NCF1MGAMMEN1KMT2ACNR2 | |
| SCHEMBL28746530 | 0.81 | NCF1 (0.56) | NCF1MGAMKMT2ACNR2CYP1A2 | |
| SCHEMBL14571970 | 0.81 | NCF1 (0.56) | NCF1MGAMMEN1KMT2ACNR2 | |
| SCHEMBL28746527 | 0.79 | NCF1 (0.53) | NCF1MGAMMEN1KMT2ACNR2 | |
| SCHEMBL28457620 | 0.79 | NCF1 (0.49) | NCF1MGAMMEN1KMT2ACNR2 | |
| SCHEMBL6602116 | 0.78 | NCF1 (0.56) | NCF1MGAMMEN1KMT2ACNR2 | |
| SCHEMBL4072980 | 0.78 | BACE1 (0.43) | NCF1CYP1A2LMNAKDM4EALDH1A1 | |
| SCHEMBL31650826 | 0.77 | NCF1 (1.00) | NCF1MGAMMEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042735-A1 | TETRAHYDROQUINOLINE, INDOLINE, AND RELATED ANILINE DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES | WYETH (US) | 2008-04-10 | — | — | WO | disclosed |