Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172207 | 0.88 | P2RY12 (0.46) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL4166527 | 0.85 | ALDH1A1 (0.47) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL3208916 | 0.82 | P2RY12 (0.62) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL4786928 | 0.81 | P2RY12 (0.44) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL3226916 | 0.80 | ALDH1A1 (0.55) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL4180538 | 0.78 | ALDH1A1 (0.41) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL4164295 | 0.78 | ALDH1A1 (0.40) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL4183233 | 0.78 | ALDH1A1 (0.43) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL4179538 | 0.78 | ALDH1A1 (0.40) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL4737215 | 0.78 | ALDH1A1 (0.38) | P2RY12ALDH1A1KDM4EL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |