Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243407 | 1.00 | DPP7 (0.42) | DPP7FDPSL3MBTL1ALDH1A1EPHX1 | |
| SCHEMBL10509650 | 0.79 | DPP7 (0.42) | DPP7FDPSL3MBTL1ALDH1A1EPHX1 | |
| SCHEMBL1428600 | 0.77 | DPP7 (0.45) | DPP7FDPSL3MBTL1ALDH1A1EPHX1 | |
| SCHEMBL3559523 | 0.76 | DPP7 (0.48) | DPP7FDPSALDH1A1GAALMNA | |
| SCHEMBL11687527 | 0.76 | DPP7 (0.48) | DPP7FDPSALDH1A1GAALMNA | |
| SCHEMBL9232932 | 0.75 | DPP7 (0.39) | DPP7FDPSL3MBTL1ALDH1A1EPHX1 | |
| SCHEMBL17331175 | 0.75 | MAOB (0.43) | DPP7FDPSL3MBTL1ALDH1A1GAA | |
| SCHEMBL14655308 | 0.75 | MAOB (0.43) | DPP7FDPSL3MBTL1ALDH1A1GAA | |
| SCHEMBL1507939 | 0.75 | DPP7 (0.39) | DPP7FDPSL3MBTL1ALDH1A1EPHX1 | |
| SCHEMBL15955855 | 0.75 | MAOB (0.43) | DPP7FDPSL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951689-A1 | P2X7 RECEPTOR ANTAGONISTS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007056046-A1 | P2X7 RECEPTOR ANTAGONISTS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-05-18 | — | — | WO | disclosed |