Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329020 | 1.00 | JAK3 (0.39) | JAK3BTKCTSSCTSKFAAH | |
| SCHEMBL4819025 | 0.90 | JAK3 (0.42) | JAK3BTKCTSSCTSKHDAC2 | |
| SCHEMBL4819038 | 0.90 | JAK3 (0.42) | JAK3BTKCTSSCTSKHDAC2 | |
| SCHEMBL838395 | 0.86 | JAK3 (0.35) | JAK3BTKCTSSCTSKFAAH | |
| SCHEMBL14796619 | 0.86 | JAK3 (0.35) | JAK3BTKCTSSCTSKFAAH | |
| SCHEMBL1808081 | 0.82 | TGFBR1 (0.42) | JAK3BTKFAAHTGFBR1MME | |
| SCHEMBL18989359 | 0.82 | TGFBR1 (0.42) | JAK3BTKFAAHTGFBR1MME | |
| SCHEMBL16165702 | 0.82 | USP2 (0.40) | CTSSCTSKLMNA | |
| SCHEMBL25360136 | 0.81 | JAK3 (0.38) | JAK3BTKCTSSFAAHTGFBR1 | |
| SCHEMBL25360128 | 0.81 | JAK3 (0.38) | JAK3BTKCTSSFAAHTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086053-A1 | HCV INHIBITORS | VIROBAY, INC. (US) | 2008-07-17 | — | — | WO | disclosed |