Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CALML3 | P27482 | 6/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778998 | 1.00 | F10 (0.44) | F10CALML3GRM2MAOAMAOB | |
| SCHEMBL4728137 | 0.95 | CALML3 (0.45) | F10CALML3GRM2MAOAMAOB | |
| SCHEMBL14870459 | 0.85 | MAOA (0.46) | F10GRM2MAOAMAOB | |
| SCHEMBL4783206 | 0.84 | GRM2 (0.53) | F10GRM2 | |
| SCHEMBL4727923 | 0.84 | GRM2 (0.53) | F10GRM2 | |
| SCHEMBL4729855 | 0.84 | SCD (0.49) | — | |
| SCHEMBL17803781 | 0.84 | SCD (0.49) | — | |
| SCHEMBL4782698 | 0.78 | F10 (0.46) | F10CALML3GRM2MAOAMAOB | |
| SCHEMBL4731364 | 0.77 | MEN1 (0.45) | RET | |
| SCHEMBL14261417 | 0.76 | CALML3 (0.52) | F10CALML3GRM2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | claimed |
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | disclosed |