Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.65 |
| ▸ | MMP14 | P50281 | 10/20 | 0.65 |
| ▸ | MMP12 | P39900 | 5/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942517 | 1.00 | MMP13 (0.65) | MMP13MMP14MMP12 | |
| Azd-1236 SCHEMBL942315 | 0.89 | MMP13 (0.74) | MMP13MMP14MMP12 | |
| SCHEMBL941741 | 0.89 | MMP13 (0.64) | MMP13MMP14MMP12 | |
| SCHEMBL941847 | 0.89 | MMP13 (0.64) | MMP13MMP14MMP12 | |
| SCHEMBL4782766 | 0.89 | MMP13 (0.64) | MMP13MMP14MMP12 | |
| Azd-1236 SCHEMBL29464251 | 0.89 | MMP13 (0.74) | MMP13MMP14MMP12 | |
| Azd-1236 SCHEMBL940419 | 0.89 | MMP13 (0.74) | MMP13MMP14MMP12 | |
| Azd-1236 SCHEMBL4091904 | 0.89 | MMP13 (0.74) | MMP13MMP14MMP12 | |
| SCHEMBL941752 | 0.89 | MMP13 (0.70) | MMP13MMP14MMP12 | |
| SCHEMBL942141 | 0.87 | MMP13 (0.75) | MMP13MMP14MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053199-A1 | COMBINATION THERAPY FOR THE TREATMENT OF RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | disclosed |