Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 2/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881603 | 0.70 | KDM5B (0.33) | TDP2KDM5B | |
| SCHEMBL9773308 | 0.70 | DAO (0.44) | CHEK1TDP2KDM5B | |
| SCHEMBL4730858 | 0.69 | NPC1 (0.42) | — | |
| SCHEMBL16936588 | 0.69 | ESR1 (0.33) | — | |
| SCHEMBL6741105 | 0.68 | NOTUM (0.36) | — | |
| SCHEMBL24573403 | 0.67 | ALDH1A1 (0.41) | — | |
| SCHEMBL13628736 | 0.67 | NPSR1 (0.33) | — | |
| SCHEMBL13525162 | 0.66 | ALDH1A1 (0.41) | — | |
| SCHEMBL22846550 | 0.66 | — | — | |
| SCHEMBL1849836 | 0.65 | POLB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |
| US-6555563-B1 | Compounds based on 2-aryl-5-(imidazol-2-yl)-1,3,4-thiadiazole or the corresponding 1,3,4-oxadiazole; selective COX-2 (cyclooxygenase-2) inhibitors; side effect reduction | MEDINOX, INC. | 2003-04-29 | — | — | US | disclosed |
| US-5310918-A | 1-aryl-substituted azole, non-linear optical material and novel molecular crystal containing same and method and module for the conversion of light wavelength using same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |