Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 6/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783410 | 0.99 | HRH3 (0.57) | HRH3SLC6A4SLC6A2SLC6A3CCR3 | |
| SCHEMBL4921656 | 0.88 | SLC6A4 (0.73) | HRH3SLC6A4SLC6A2SLC6A3CCR3 | |
| SCHEMBL4921696 | 0.87 | SLC6A4 (0.75) | HRH3SLC6A4SLC6A2SLC6A3L3MBTL3 | |
| Trifluoroacetic Acid SCHEMBL4925697 | 0.84 | SLC6A4 (0.70) | HRH3SLC6A4SLC6A2SLC6A3L3MBTL3 | |
| SCHEMBL4784879 | 0.82 | HRH3 (0.65) | HRH3SLC6A4MEN1HPGDTSHR | |
| SCHEMBL4918880 | 0.82 | SLC6A4 (0.72) | HRH3SLC6A4SLC6A2SLC6A3L3MBTL3 | |
| SCHEMBL4925879 | 0.72 | HRH3 (1.00) | HRH3SLC6A4 | |
| SCHEMBL4735283 | 0.72 | HRH3 (1.00) | HRH3SLC6A4 | |
| SCHEMBL4919787 | 0.71 | SLC6A4 (0.59) | HRH3SLC6A4SLC6A2CCR3 | |
| SCHEMBL4733830 | 0.71 | HRH3 (0.83) | HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064036-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-29 | — | — | WO | claimed |