Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919233 | 0.88 | HRH3 (0.85) | HRH3SLC6A4EPHX2SLC6A9 | |
| Trifluoroacetic Acid SCHEMBL4924383 | 0.84 | HRH3 (0.79) | HRH3SLC6A4SLC6A9 | |
| SCHEMBL4783410 | 0.83 | HRH3 (0.57) | HRH3SLC6A4GPR183MEN1HPGD | |
| SCHEMBL4783587 | 0.82 | HRH3 (0.56) | HRH3SLC6A4MEN1HPGDTSHR | |
| SCHEMBL4733830 | 0.79 | HRH3 (0.83) | HRH3SLC6A4SLC6A9 | |
| SCHEMBL4735283 | 0.79 | HRH3 (1.00) | HRH3SLC6A4EPHX2SLC6A9 | |
| SCHEMBL4925879 | 0.79 | HRH3 (1.00) | HRH3SLC6A4EPHX2SLC6A9 | |
| Trifluoroacetic Acid SCHEMBL4916696 | 0.77 | HRH3 (0.78) | HRH3SLC6A4SLC6A9 | |
| SCHEMBL4732424 | 0.73 | SLC6A4 (0.75) | HRH3SLC6A4HTR1ASLC6A9 | |
| SCHEMBL4921696 | 0.71 | SLC6A4 (0.75) | HRH3SLC6A4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064036-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-29 | — | — | WO | claimed |