Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783605 | 1.00 | CYP19A1 (0.42) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| SCHEMBL1109891 | 0.94 | CHRM2 (0.37) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| SCHEMBL1109893 | 0.94 | CHRM2 (0.37) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| Bromide SCHEMBL2877676 | 0.93 | CHRM2 (0.36) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| Bromide SCHEMBL2877682 | 0.93 | CHRM2 (0.36) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| SCHEMBL4783528 | 0.93 | LMNA (0.37) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| SCHEMBL4743392 | 0.93 | LMNA (0.35) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| SCHEMBL4801959 | 0.93 | LMNA (0.35) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| SCHEMBL4743395 | 0.93 | LMNA (0.35) | CYP19A1CHRM3MEN1KMT2ALMNA | |
| SCHEMBL4801950 | 0.93 | LMNA (0.35) | CYP19A1CHRM3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | claimed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |