Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11172536 | 0.85 | MEN1 (0.54) | GLO1MEN1KMT2AMAPTLMNA | |
| SCHEMBL21470279 | 0.85 | MEN1 (0.54) | GLO1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11174483 | 0.84 | MAPT (0.53) | GLO1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11174486 | 0.84 | MAPT (0.53) | GLO1MEN1KMT2AMAPTLMNA | |
| SCHEMBL4744535 | 0.84 | F2 (0.50) | F2PLGPRSS1MEN1KMT2A | |
| SCHEMBL4799775 | 0.81 | F2 (0.52) | F2PLGPRSS1MEN1KMT2A | |
| SCHEMBL4741524 | 0.81 | F2 (0.52) | F2PLGPRSS1MEN1KMT2A | |
| SCHEMBL11174492 | 0.78 | NPSR1 (0.48) | F2PLGPRSS1MEN1KMT2A | |
| SCHEMBL4786977 | 0.78 | F2 (0.51) | F2PLGPRSS1MAPTLMNA | |
| SCHEMBL4786981 | 0.78 | F2 (0.51) | F2PLGPRSS1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099415-A1 | NOVEL SUBSTITUTED BIS-1, 2, 4-TRIOXANES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-08-21 | — | — | WO | disclosed |