Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786981 | 1.00 | F2 (0.51) | F2PLGPRSS1PTGS2MAPT | |
| SCHEMBL4540567 | 0.91 | F2 (0.45) | F2PLGPRSS1MAPTHPGD | |
| SCHEMBL4540564 | 0.91 | F2 (0.45) | F2PLGPRSS1MAPTHPGD | |
| SCHEMBL4741524 | 0.90 | F2 (0.52) | F2PLGPRSS1MAPTHPGD | |
| SCHEMBL4799775 | 0.90 | F2 (0.52) | F2PLGPRSS1MAPTHPGD | |
| SCHEMBL4744535 | 0.85 | F2 (0.50) | F2PLGPRSS1PTGS2MAPT | |
| SCHEMBL11159505 | 0.82 | KDM4E (0.53) | F2PLGPRSS1MAPTHPGD | |
| SCHEMBL11156770 | 0.82 | KDM4E (0.53) | F2PLGPRSS1MAPTHPGD | |
| SCHEMBL2203941 | 0.82 | TERT (0.49) | F2PLGPRSS1MAPTHPGD | |
| SCHEMBL2203937 | 0.82 | TERT (0.49) | F2PLGPRSS1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099415-A1 | NOVEL SUBSTITUTED BIS-1, 2, 4-TRIOXANES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-08-21 | — | — | WO | disclosed |