SCHEMBL478395

SCHEMBL478395

COC(C)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13093806 1.00
Chloromethane SCHEMBL8094945 0.95
SCHEMBL5933999 0.95
SCHEMBL6912285 0.95
Chloromethane SCHEMBL8502682 0.91
Chloroform SCHEMBL8784909 0.76
SCHEMBL975868 0.76
Methoxymethane SCHEMBL7518966 0.74
SCHEMBL62080 0.74
SCHEMBL559564 0.73 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960291-A Preparation method of long-chain haloalkyl styrene polymer 南京大学 2023-04-14 CN claimed
CN-113185501-A Efficient total synthesis method and application of natural product schaftoside 中国科学院生态环境研究中心 2021-07-30 CN claimed
CN-107126660-B Composition containing fluoroketone 中化蓝天集团有限公司 2021-02-05 CN claimed
CN-112174938-A 4-indole-2-aminopyrimidine compounds and application thereof 浙江工业大学 2021-01-05 CN claimed
CN-111807984-A Novel synthetic process of dimethachlor 江苏云帆化工有限公司 2020-10-23 CN claimed
CN-106810444-B A kind of method of chlorobenzoyl chloride and halogenated alkane reaction generation ester 中国科学院大连化学物理研究所 2018-09-04 CN claimed
CN-107126660-A A kind of composition for including fluorinated ketones contained 中化蓝天集团有限公司 2017-09-05 CN claimed
CN-104725327-B A kind of environment-friendly preparation method of erlotinib Hydrochloride 山东大学 2017-08-25 CN claimed
CN-106892821-A A kind of preparation method of 3,4- bis- (2- methoxy ethoxies) ethyl benzoate 浙江九洲药业股份有限公司 2017-06-27 CN claimed
CN-106810444-A A kind of method of chlorobenzoyl chloride and halogenated alkane reaction generation ester 中国科学院大连化学物理研究所 2017-06-09 CN claimed
CN-102659692-A Double-linked Erlotinib and preparation method thereof ZHENGZHOU TETRANOV PHARMACEUTICAL TECHNOLOGY CO LTD 2012-09-12 CN claimed
CN-101463013-B Preparation of erlotinid hydrochloride PARLING SHANGHAI PHARMATECH CO LTD 2011-06-22 CN claimed
CN-101463013-A Preparation of erlotinid hydrochloride PARLING SHANGHAI PHARM TECHNOL (CN) 2009-06-24 CN claimed
JP-2008509134-A 2008-03-27 JP claimed
EP-1809301-A2 PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES Pharmasset, Inc. (US) 2007-07-25 EP claimed
EP-1781629-A1 NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) 2007-05-09 EP claimed
US-7144876-B2 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. (US) 2006-12-05 US claimed
US-20060122146-A1 Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives GILEAD SCIENCES, INC. 2006-06-08 US claimed
WO-2006031725-A2 PREPARATION OF 2'­FLUORO-2'- ALKYL- SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES PHARMASSET, INC. (US) 2006-03-23 WO claimed
WO-2006014087-A1 NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DONG WHA PHARMACEUTICAL. IND. CO., LTD. (KR) 2006-02-09 WO claimed