Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781513 | 0.93 | PIK3CA (0.42) | HTR2APIK3CAKDM4EMEN1KMT2A | |
| SCHEMBL4783926 | 0.91 | HRH4 (0.44) | PIK3CASMN1; SMN2MTORCYP2C19ADORA3 | |
| SCHEMBL4785845 | 0.91 | HRH4 (0.44) | PIK3CASMN1; SMN2MTORCYP2C19ADORA3 | |
| SCHEMBL4846093 | 0.91 | HRH4 (0.44) | PIK3CASMN1; SMN2MTORCYP2C19ADORA3 | |
| SCHEMBL4782301 | 0.89 | PIK3CA (0.43) | PIK3CAMEN1KMT2AMTORADORA3 | |
| SCHEMBL4784653 | 0.88 | ADORA3 (0.43) | PIK3CASMN1; SMN2MTORCYP2C19ADORA3 | |
| SCHEMBL4784808 | 0.88 | PIK3CA (0.39) | PIK3CAMTORADORA3ADORA1 | |
| SCHEMBL4784093 | 0.87 | PIK3CA (0.43) | PIK3CAKMT2AALDH1A1MTOR | |
| SCHEMBL4785240 | 0.87 | PIK3CA (0.58) | PIK3CAKMT2AMTOR | |
| SCHEMBL4782727 | 0.87 | PIK3CA (0.58) | PIK3CAKMT2AMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |