SCHEMBL4784026

SCHEMBL4784026

CCCCC[SiH](CCCCC)CCCCCl

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.63
ALDH1A1 P00352 4/20 0.63
TDP1 Q9NUW8 2/20 0.53
THRB P10828 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 3/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
FAAH O00519 2/20 0.33
PLA2G1B P04054 1/20 0.31
HSP90AA1 P07900 1/20 0.31
RAD52 P43351 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL416766 0.85 TSHR (0.50) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL17090806 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL17090843 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL475823 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL17090793 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL17090787 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL367967 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL10416460 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL17090779 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA
SCHEMBL1033088 0.82 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008063134-A1 METHOD OF PRODUCING A PATTERN OF DISCRIMINATIVE WETTABILITY AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed