Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 12/20 | 0.41 |
| ▸ | MTOR | P42345 | 9/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783022 | 0.91 | PIK3CA (0.49) | PIK3CAMTORPIK3CG | |
| SCHEMBL4784674 | 0.84 | HRH4 (0.43) | KDM4EALDH1A1CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL4786254 | 0.84 | PIK3CA (0.47) | PIK3CAMTORPIK3CG | |
| SCHEMBL4782727 | 0.82 | PIK3CA (0.58) | PIK3CAMTORPIK3CG | |
| SCHEMBL4785240 | 0.82 | PIK3CA (0.58) | PIK3CAMTORPIK3CG | |
| SCHEMBL4884098 | 0.80 | PIK3CA (0.45) | PIK3CAMTORPIK3CG | |
| SCHEMBL4782447 | 0.80 | HRH4 (0.36) | KDM4EALDH1A1ADORA2AADORA1GRM5 | |
| SCHEMBL4782277 | 0.79 | ADORA2A (0.35) | PIK3CAMTORPIK3CGALDH1A1ADORA2A | |
| SCHEMBL4785912 | 0.79 | PIK3CA (0.40) | PIK3CAMTORPIK3CGHRH3 | |
| SCHEMBL14161658 | 0.79 | MTOR (0.46) | PIK3CAMTORPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |