Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 5/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.33 |
| ▸ | MTOR | P42345 | 5/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161656 | 0.90 | PIK3CA (0.40) | PIK3CAMTORPIK3CG | |
| SCHEMBL14161859 | 0.85 | PIK3CA (0.38) | PIK3CAMTORPIK3CGCHEK1 | |
| SCHEMBL14161651 | 0.81 | PDE5A (0.35) | PIK3CAMTORPIK3CGPRMT5WDR77 | |
| SCHEMBL14161615 | 0.80 | NAPEPLD (0.39) | ADORA2AADORA1GRM5PIK3CAMTOR | |
| SCHEMBL4785757 | 0.80 | PIK3CA (0.36) | ADORA1PIK3CAMTORCHEK1JAK2 | |
| SCHEMBL4784083 | 0.79 | PIK3CA (0.41) | ADORA2AADORA1GRM5PIK3CAMTOR | |
| SCHEMBL4784163 | 0.77 | PIK3CA (0.35) | ADORA2AADORA1PIK3CAPRMT5WDR77 | |
| SCHEMBL14161674 | 0.77 | PIK3CA (0.35) | ADORA2AADORA1PIK3CAPRMT5WDR77 | |
| SCHEMBL4784229 | 0.77 | PIK3CA (0.35) | PIK3CAMTORPIK3CGCHEK1JAK2 | |
| SCHEMBL4784674 | 0.76 | HRH4 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |