Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784691 | 0.94 | AOC3 (0.41) | AOC3ESR1ESR2PIK3CAPFKFB3 | |
| SCHEMBL4783343 | 0.94 | AOC3 (0.41) | AOC3ESR1ESR2PIK3CAPFKFB3 | |
| SCHEMBL4784483 | 0.89 | ESR1 (0.38) | AOC3ESR1ESR2PIK3CAPFKFB3 | |
| SCHEMBL4785552 | 0.85 | PIK3CA (0.42) | ESR1ESR2PIK3CAPFKFB3PIK3CB | |
| SCHEMBL4785055 | 0.84 | PIK3CA (0.39) | ESR1ESR2PIK3CAPFKFB3PIK3CB | |
| SCHEMBL4785045 | 0.84 | PIK3CA (0.39) | ESR1ESR2PIK3CAPFKFB3PIK3CB | |
| SCHEMBL4784132 | 0.83 | PIK3CA (0.44) | ESR1ESR2PIK3CAPFKFB3MTOR | |
| SCHEMBL4884094 | 0.82 | PIK3CA (0.44) | ESR1ESR2PIK3CAPFKFB3PIK3CB | |
| SCHEMBL4784160 | 0.82 | PIK3CA (0.42) | ESR1ESR2PIK3CAPFKFB3MTOR | |
| SCHEMBL4782625 | 0.82 | PIK3CA (0.40) | ESR1ESR2PIK3CAPFKFB3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |