Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783923 | 0.96 | HRH4 (0.43) | ADORA3ADORA1HRH4PIK3CAMTOR | |
| SCHEMBL4782297 | 0.89 | PIK3CA (0.43) | ADORA3ADORA1HRH4PIK3CAMTOR | |
| SCHEMBL4784015 | 0.88 | HTR2A (0.44) | ADORA3ADORA1PIK3CAMTORESR2 | |
| SCHEMBL4784804 | 0.87 | ESR1 (0.41) | ADORA3ADORA1HRH4PIK3CAMTOR | |
| SCHEMBL4784088 | 0.87 | PIK3CA (0.43) | PIK3CAMTORESR2ESR1PIK3CG | |
| SCHEMBL4781508 | 0.86 | PIK3CA (0.42) | ADORA3ADORA1HRH4PIK3CAMTOR | |
| SCHEMBL4848936 | 0.86 | PIK3CA (0.47) | PIK3CAMTOR | |
| SCHEMBL4785905 | 0.86 | ESR1 (0.44) | PIK3CAMTORESR2ESR1PIK3CG | |
| SCHEMBL4782788 | 0.86 | PIK3CA (0.42) | PIK3CAMTORESR2ESR1PFKFB3 | |
| SCHEMBL4884094 | 0.86 | PIK3CA (0.44) | PIK3CAMTORESR2ESR1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |