Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781508 | 0.93 | PIK3CA (0.42) | HTR2APIK3CAMEN1KMT2AMTOR | |
| SCHEMBL4783923 | 0.92 | HRH4 (0.43) | PIK3CASMN1; SMN2MTORCYP2C19ESR1 | |
| SCHEMBL4782297 | 0.90 | PIK3CA (0.43) | PIK3CAMTORESR1ESR2ADORA3 | |
| SCHEMBL4784640 | 0.88 | ADORA3 (0.43) | PIK3CAMTORESR1ESR2ADORA3 | |
| SCHEMBL4784804 | 0.88 | ESR1 (0.41) | PIK3CAMTORESR1ESR2ADORA3 | |
| SCHEMBL4784088 | 0.88 | PIK3CA (0.43) | PIK3CAKMT2AALDH1A1MTORESR1 | |
| SCHEMBL4782788 | 0.87 | PIK3CA (0.42) | PIK3CAALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL4782724 | 0.87 | PIK3CA (0.57) | PIK3CAMTOR | |
| SCHEMBL4884094 | 0.87 | PIK3CA (0.44) | PIK3CAMTORESR1ESR2 | |
| SCHEMBL4784160 | 0.87 | PIK3CA (0.42) | PIK3CAMTORESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |