Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.77 |
| ▸ | MMP14 | P50281 | 8/20 | 0.70 |
| ▸ | MMP12 | P39900 | 5/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940885 | 1.00 | MMP13 (0.77) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL942026 | 0.90 | MMP13 (0.85) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL4779687 | 0.90 | MMP13 (0.85) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL941182 | 0.89 | MMP13 (0.78) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL4785010 | 0.89 | MMP13 (0.78) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL942378 | 0.89 | MMP13 (0.78) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL941464 | 0.89 | MMP13 (0.81) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL942359 | 0.89 | MMP13 (0.82) | MMP13MMP14MMP12KCNH2 | |
| SCHEMBL943609 | 0.87 | MMP13 (0.80) | MMP13MMP14MMP12 | |
| SCHEMBL12911600 | 0.87 | MMP13 (0.72) | MMP13MMP14MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053199-A1 | COMBINATION THERAPY FOR THE TREATMENT OF RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | disclosed |